Wegovy does not appear to affect the effectiveness of oral contraceptive pills. However, Mounjaro has been shown to reduce their effectiveness, likely due to interference with the pill’s absorption in the digestive system. While the exact mechanism is unclear, it is believed that Mounjaro may impair the absorption of hormones in the gut.
Therefore, we recommend that women using Mounjaro alongside the pill use additional barrier contraception methods, such as condoms. This precaution is unnecessary for women using Wegovy.
If you are planning to become pregnant, we advise discontinuing Mounjaro at least two months before trying to conceive.